BioMCP

Overview

A real, actively maintained (628 GitHub stars at review time, pushed the same day as this review) MCP server, also distributed as the `biomcp-cli` CLI binary, that reaches roughly 30 trusted biomedical sources through one command grammar: PubMed/PubTator3, ClinVar, ClinicalTrials.gov, OncoKB, Reactome, and more, confirmed directly from the project's own README and `server.json`. ClinVar and ClinicalTrials.gov are the two sources this registry's admission bar cares about most directly: clinical variant significance classification and clinical-trial matching are concrete genomics and health-research workflows, not vague health-adjacent branding.

MIT licence confirmed by direct fetch of the repository's own root `LICENSE` file (Copyright 2025 Ian Maurer), not from GitHub's derived metadata alone.

Recorded as a marginal fit, plainly: BioMCP wraps public genomics and clinical databases directly rather than implementing or wrapping a named GA4GH API specification, and it carries no GA4GH-aligned (or any) access-control layer, since it queries open public APIs. It clears this registry's admission bar on the weaker of the two relevance tests, a real genomics/health data source exposed as MCP tools, with a concrete rather than vague relevance fact, but not the stronger named-GA4GH-standard or GA4GH-aligned-access-control test.

Details

Licence

MIT

Version

0.8.25

Category

Other GA4GH-standard or genomics/health data source

Homepage

https://biomcp.org/

Repository

https://github.com/genomoncology/biomcp

Maintainers

Susheel Varma (@susheel, GA4GH AI Workstream / Sage Bionetworks)

Keywords

clinvarclinicaltrialspubmedoncokbbiomedicalmcp-server

GA4GH standards

other

Safety classification

No safety classification has been submitted for this entry.

Server manifest

Server name

io.github.genomoncology/biomcp

Server version

0.8.25

Implements

other

Install

{
  "mcpServers": {
    "io.github.genomoncology/biomcp": {
      "command": "uvx",
      "args": [
        "biomcp-cli@0.8.25",
        "serve"
      ]
    }
  }
}

{
  "mcpServers": {
    "io.github.genomoncology/biomcp": {
      "command": "uvx",
      "args": [
        "biomcp-cli@0.8.25",
        "serve"
      ]
    }
  }
}

{
  "mcpServers": {
    "io.github.genomoncology/biomcp": {
      "command": "uvx",
      "args": [
        "biomcp-cli@0.8.25",
        "serve"
      ]
    }
  }
}

{
  "servers": {
    "io.github.genomoncology/biomcp": {
      "command": "uvx",
      "args": [
        "biomcp-cli@0.8.25",
        "serve"
      ]
    }
  }
}

{
  "mcpServers": {
    "io.github.genomoncology/biomcp": {
      "command": "uvx",
      "args": [
        "biomcp-cli@0.8.25",
        "serve"
      ]
    }
  }
}

{
  "mcpServers": {
    "io.github.genomoncology/biomcp": {
      "command": "uvx",
      "args": [
        "biomcp-cli@0.8.25",
        "serve"
      ]
    }
  }
}

{
  "mcp": {
    "io.github.genomoncology/biomcp": {
      "type": "local",
      "command": [
        "uvx",
        "biomcp-cli@0.8.25",
        "serve"
      ],
      "enabled": true
    }
  }
}

Provenance

Created

2026-09-08T00:00:00.000Z

Updated

2026-09-08T00:00:00.000Z

Last verified

2026-09-08T00:00:00.000Z