GA4GH MCP Server (DNAstack)

Exposes 57 tools across the GA4GH Registry, WES, TES, TRS, Beacon v2, DRS, htsget, refget, and Data Connect as one MCP server.

Unsigned

Overview

A single MCP server, published under the DNAstack GitHub organisation, that exposes the breadth of the GA4GH standards ecosystem to AI clients such as Claude Desktop and Claude Code: 57 tools spanning Registry discovery (12), WES (6), TES (5), TRS (8), Beacon v2 (7), DRS (3), htsget (4), refget (3), Data Connect (5), and combined Service Info/Registry (4), confirmed directly from the project's own README rather than assumed from its name. This is the strongest possible fit for this registry's mcp-server admission bar: it implements, not merely references, eight-plus named GA4GH API specifications as MCP tool groups.

The repository (created 2026-04-17, last pushed 2026-08-05, public, non-fork) is not an impersonation or a coincidental name match: Marc Fiume, co-chair of this very GA4GH AI Workstream, is a confirmed contributor (`mfiume`, 22 contributions) on the repository itself. A hosted instance is live at a Cloud Run endpoint, gated by a per-user API key passed as `Authorization: Bearer`, with self-hosting documented for Docker and Google Cloud Run.

Licensing note: the repository carries no root LICENSE file, so GitHub's own repository metadata reports no licence. Checked directly against the project's own packaging manifest (`pyproject.toml`) rather than relying on that absence, the `[project]` table declares `license = "Apache-2.0"` explicitly, the project's own authoritative self-declaration, the same convention this registry already accepts elsewhere (a plugin manifest's own `license` field) when no separate LICENSE file exists. Recorded here as `Apache-2.0` on that basis, not invented.

Not a marginal call: this entry implements named GA4GH standards directly, the strongest of the two relevance tests this registry's PRD defines for the mcp-servers type.

Details

Licence: Apache-2.0
Version: 0.1.0
Category: Other GA4GH-standard or genomics/health data source
Homepage: https://github.com/DNAstack/ga4gh-mcp-server
Repository: https://github.com/DNAstack/ga4gh-mcp-server
Maintainers: Susheel Varma (@susheel, GA4GH AI Workstream / Sage Bionetworks)
Keywords: ga4ghtrsdrsbeaconhtsgetrefgetdata-connectwestesmcp-server
GA4GH standards: trsdrsbeaconhtsgetrefgetdata-connectwestesservice-infoservice-registry

Safety classification

No safety classification has been submitted for this entry.

Server manifest

Server name: io.github.dnastack/ga4gh-mcp-server
Server version: 0.1.0
Implements: trs, drs, beacon, htsget, refget, data-connect, wes, tes, service-info, service-registry

Install

{
  "mcpServers": {
    "io.github.dnastack/ga4gh-mcp-server": {
      "type": "http",
      "url": "https://ga4gh-mcp-662019113068.us-central1.run.app/mcp/"
    }
  }
}

{
  "mcpServers": {
    "io.github.dnastack/ga4gh-mcp-server": {
      "type": "http",
      "url": "https://ga4gh-mcp-662019113068.us-central1.run.app/mcp/"
    }
  }
}

{
  "mcpServers": {
    "io.github.dnastack/ga4gh-mcp-server": {
      "type": "http",
      "url": "https://ga4gh-mcp-662019113068.us-central1.run.app/mcp/"
    }
  }
}

Open in Cursor

{
  "servers": {
    "io.github.dnastack/ga4gh-mcp-server": {
      "type": "http",
      "url": "https://ga4gh-mcp-662019113068.us-central1.run.app/mcp/"
    }
  }
}

{
  "mcpServers": {
    "io.github.dnastack/ga4gh-mcp-server": {
      "type": "http",
      "url": "https://ga4gh-mcp-662019113068.us-central1.run.app/mcp/"
    }
  }
}

{
  "mcpServers": {
    "io.github.dnastack/ga4gh-mcp-server": {
      "type": "http",
      "url": "https://ga4gh-mcp-662019113068.us-central1.run.app/mcp/"
    }
  }
}

Provenance

Created: 2026-09-08T00:00:00.000Z
Updated: 2026-09-08T00:00:00.000Z
Last verified: 2026-09-08T00:00:00.000Z