Geneformer
ctheodoris/geneformer@1f7fbaeSingle-cell transcriptome foundation model for context-aware network-biology predictions, from the Broad Institute / Theodoris lab.
Overview
Geneformer is a foundational transformer model pretrained on a large-scale corpus of human single-cell transcriptomes (Genecorpus-30M, and now Genecorpus-104M for the V2 model), developed by the Theodoris lab at the Broad Institute. It enables context-aware predictions in network biology settings with limited data, including zero-shot in-silico perturbation and gene/cell-state classification, and is also listed on the Chan Zuckerberg Initiative's Virtual Cells Platform.
Registry note on model_card_uri: this points to the model's standard Hugging Face model card (its README carries a license: apache-2.0 YAML tag, confirmed directly), not a GA4GH Genomic AI Model Card v0.6.0-formatted document. No model has yet published a card in the GA4GH v0.6.0 format, since it is a newly drafted specification.
Details
- Licence
- Apache-2.0
- Version
- V2 (Genecorpus-104M)
- Category
- Genomic foundation model
- Homepage
- https://huggingface.co/ctheodoris/Geneformer
- Repository
- https://huggingface.co/ctheodoris/Geneformer
- Maintainers
- Susheel Varma (@susheel, GA4GH AI Workstream / Sage Bionetworks)
- Keywords
- single-celltranscriptomicsgenomicsfoundation-modelnetwork-biology
Publisher
- Published by
- Christina Theodoris (Hugging Face user) profile ↗
- Upstream name
- Geneformer
- Upstream version
1f7fbae(Hugging Face revision)- Version date
Safety classification
No safety classification has been submitted for this entry.
Model Card
View the upstream model card ↗
- Hosting
- huggingface
- Access
- https://huggingface.co/ctheodoris/Geneformer
Model details
- Reference precision
fp32- Weights
- Open (downloadable without approval)
- Weights licence
- Apache-2.0
Mirrored data last synced from the Model Card at 2026-09-04T11:05:00.000Z. See the linked card for the authoritative, live version.
Provenance
- Created
- Updated
- Last verified