GA4GH AI RegistryAI Workstream

Models

HyenaDNA

Qualified idlongsafari/hyenadna-large-1m-seqlen-hf@0a629ab

Long-range genomic foundation model, pretrained at single-nucleotide resolution on context lengths up to 1 million tokens.

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Overview

HyenaDNA is a long-range genomic foundation model from the Hazy Research lab at Stanford, pretrained at single-nucleotide resolution on context lengths of up to 1 million tokens, substantially longer than prior genomic language models. It is released as a family of checkpoints (tiny/small/medium/large) at varying sequence lengths.

Licence note: the weights are licensed BSD-3-Clause, as declared in the Hugging Face model card metadata (LongSafari/hyenadna-large-1m-seqlen-hf, checked 2026-09-30). The training and inference code in github.com/HazyResearch/hyena-dna is separately licensed Apache-2.0.

Registry note on model_card_uri: this points to the model's standard Hugging Face model card, not a GA4GH Genomic AI Model Card v0.6.0-formatted document. No model has yet published a card in the GA4GH v0.6.0 format, since it is a newly drafted specification.

Details

Licence
BSD-3-Clause
Version
large-1m-seqlen
Category
Genomic foundation model
Homepage
https://huggingface.co/LongSafari/hyenadna-large-1m-seqlen-hf
Repository
https://github.com/HazyResearch/hyena-dna
Maintainers
Susheel Varma (@susheel, GA4GH AI Workstream / Sage Bionetworks)
Keywords
dnagenomicsfoundation-modellong-rangesingle-nucleotide-resolution

Publisher

Published by
LongSafari (HyenaDNA authors) (Hugging Face organisation) profile ↗
Upstream name
hyenadna-large-1m-seqlen-hf
Upstream version
0a629ab (Hugging Face revision)
Version date

Safety classification

No safety classification has been submitted for this entry.

What the safety levels mean

Model Card

View the upstream model card ↗

Hosting
huggingface
Access
https://huggingface.co/LongSafari/hyenadna-large-1m-seqlen-hf

Model details

Parameters
54.6M (54,556,768)
Reference precision
fp32
Weights
Open (downloadable without approval)
Weights licence
BSD-3-Clause

Mirrored data last synced from the Model Card at 2026-09-04T11:05:00.000Z. See the linked card for the authoritative, live version.

Provenance

Created
Updated
Last verified