AWS Kiro Clinical Interoperability skill

Qualified idaws-samples/sample-kiro-power-life-sciences@1e776e2

Marginal fit: a Kiro steering-file guide (not an executable tool) to FHIR, HL7 v2, and OMOP CDM, including mapping genomic variants into FHIR Observation/DiagnosticReport resources.

Unsigned
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Overview

The clinical-interoperability skill from AWS's Kiro for Life Sciences bundle. Its content is real and concretely on-standard: FHIR resource types (Patient, Observation, Condition, DiagnosticReport, MolecularSequence) including a documented pattern for mapping VCF fields into FHIR Observation.component elements per the FHIR Genomics Implementation Guide, HL7 v2 ORU/ADT/ORM message structure with a worked example encoding a BRCA1 pathogenic-variant result, and OMOP CDM guidance -- verified by direct fetch of the skill file itself. This entry is marked marginal, not clean, for a specific, disclosed reason: unlike the other skill entries seeded in this pass (which wrap an executable tool, API, or script with a defined input/output contract), this is a Kiro steering document (inclusion: manual frontmatter) -- reference guidance injected into an agent's context, with no script, API call, or defined return schema of its own. The inputs/outputs recorded below are this registry's own reasonable characterisation of a guidance-lookup skill, not a contract declared by the source. Terms check: the repository's root LICENSE.txt is MIT-0 (MIT No Attribution), confirmed by direct fetch; MIT-0 is not on this registry's SPDX allow-list (schemas/vocab/licenses.json), so this entry records license: "other" with license_url pointing at that LICENSE.txt rather than an approximate SPDX match, per this registry's own convention for a real but un-listed licence. The candidate research note that led to this check described '10 named domain skills plus 16 steering workflows' including a 'gene-disease-associations' workflow chaining ClinVar to OMIM to HPO; direct inspection confirmed both the count and this specific skill/steering-file split (kiro-life-sciences/skills/ holds 10 domain-guidance files including this one, kiro-life-sciences/steering/ holds 16 workflow files including gene-disease-associations.md and fhir-clinical-integration.md), and separately confirmed the repository also ships genuine MCP servers (e.g. life-sciences-genomics, wrapping NCBI/Ensembl/ClinVar/GEO/SRA) as a distinct component from these skill/steering files. No slug collision with any existing entry in this registry.

Details

Licence
other (full text)
Version
1e776e2
Category
Data curation
Homepage
https://github.com/aws-samples/sample-kiro-power-life-sciences/tree/main/kiro-life-sciences
Repository
https://github.com/aws-samples/sample-kiro-power-life-sciences
Maintainers
Susheel Varma (@susheel, GA4GH AI Workstream / Sage Bionetworks)
Keywords
fhirhl7v2omop-cdmclinical-interoperabilityaws-kirogenomics-in-fhir

Publisher

Published by
AWS Samples (GitHub organisation) profile โ†—
Upstream name
sample-kiro-power-life-sciences
Upstream version
1e776e2 (Commit)
Version date

Safety classification

No safety classification has been submitted for this entry.

What the safety levels mean

Skill

Human oversight
recommended
Provenance logging
No
Evaluation criteria
https://github.com/aws-samples/sample-kiro-power-life-sciences/tree/main/kiro-life-sciences/tests
Source
https://github.com/aws-samples/sample-kiro-power-life-sciences.git (kiro-life-sciences/skills/clinical-interoperability.md)

Inputs

  • data_exchange_scenario (string) โ€” A description of the clinical or genomic data-exchange task, e.g. mapping a VCF variant into a FHIR Observation, parsing an HL7 v2 ORU message, or querying an OMOP CDM table. Not a declared API contract -- inferred by this registry from the guidance the skill provides.

Outputs

  • interoperability_guidance (string) โ€” Implementation guidance, resource/message/table mappings, and example payloads for the requested clinical-data-exchange standard. Not a declared return schema -- inferred by this registry from the guidance the skill provides.

Provenance

Created
Updated
Last verified